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Although there are no adequate and well-controlled studies using hydrochlorothiazide in pregnancy, thiazide diuretics may cause an increased risk of congenital defects. As directed, with meals, early in the day to avoid nocturia. If you are or will be breast-feeding while you use Hydrochlorothiazide. Some of the side effects that may occur while taking Microzide include black, tarry stools blood in urine or stools cough or hoarseness fever or chills joint pain lower back or side pain painful or difficult urination.

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