Prednisone is the most commonly-prescribed oral corticosteroid. It may still pose a risk to the infant. Deltasone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases. Prednisolone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisone may interact with estrogens and phenytoin.