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The shortest possible time necessary to relieve your symptoms. Celecoxib is a non-steroidal anti-inflammatory drug. For each patient. Celebrex is used to reduce pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Fluconazole increases the concentration of Celecoxib in the body by inhibiting the breakdown of Celecoxib in the body by inhibiting the breakdown of Celecoxib in the liver. Celebrex is used to decrease growths found in the intestines of persons with a family history of this condition.