Ryan Lewis noticed: "Nolvadex, is the trade name for the drug Tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties. Bodybuilders who take Nolvadex also use anabolic steroids and other performance enhancing drugs, frequently use Nolvadex in order to block estrogen that result as a side effect from using drugs. Tamoxifen citrate works by competitively binding to target estrogen sites like those at the breast. Since it helps in the burning of fat. The Tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved. Nolvadex can aid in preventing edema, gynecomastia, and female pattern fat distribution, all of which might occur when a man's estrogen levels are too high. Athletes who have a high risk of developing breast cancer."