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Prednisone and Prednisolone are considered to be intermediate acting steroids, meaning that a dose lasts about a day or a day and a half. You may need a dose adjustment or special tests to safely take Prednisolone. Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisone to Prednisolone is impaired. You should tell your doctor about all of your medical conditions and about all other medicines you are using. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Corticosteroids reduce the normal response of the immune system to attack by micro-organisms, it should be ensured that if antibiotics are required, that they are given in effective doses.
