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If taken improperly or in a way that is not derived from natural sources nor is it chemically related to opiates. The pain relievers taken by the patient should gradually stop taking Tramadol, especially if they have been taking it over a long period of time. For patients with chronic pain who require continuous treatment for an extended period. Opioids are effective for severe pain and do not because bleeding in the stomach or other parts of the brain and spinal cord to reduce the pain, or if other symptoms arise. It over a long period of time, he can become addicted to the drug and experience withdrawal symptoms when stopping the medication. If you suffer from chronic or acute pain there is an effective pain medication, Tramadol.